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Kate Chopin s The Yellow Wallpaper - 1208 Words

What were the consequences for being a woman back in the 1800’s? Not to mention, for centuries women have always been placed under control of men, whereas they were more known to be housewives. In addition, women were only allowed to do domestic work, throughout history, women have fought for the equal right. Similarly, â€Å"The Storm† and â€Å"The Yellow Wallpaper† that indicates perfect examples of domestic. However, in the two short stories â€Å"Story of an Hour† Louise Mallard is the protagonist of Kate Chopin s 1984 short story and â€Å"The Yellow Wallpaper† Jennie is the protagonist, focus on women’s plight near the 19th century. The era around the time is a modern society when women were still treated as second-class citizens. For instance, the two women with the stories, share similarities, but different considering how they dealt with the problems in their lives. In addition to this around this time women were simple with men t hat they did not happen with, but only stood in their marriages for the kids and it was not common to be alone without having a husband to be in charged of the house.Men were allowed to own property including the woman and all of her inheritance, they could get an education (like most women couldn t, and they could have a lot of jobs that women couldn t. In â€Å"The Yellow Wallpaper† by Charlotte Perkins Gilman, the unnamed female protagonist is going through a rough time in her life has been in a difficult situation being a woman who is not in control ofShow MoreRelatedKate Chopin s The Yellow Wallpaper1415 Words   |  6 PagesVictorian era were Kate Chopin and Charlotte Perkins Gilman. The Victorian era brought out many different themes of freedom, confinement, and inequity. The Victorian themes can be seen in Kate Chopin’s writing called, â€Å"The Story of an Hour† and Charlotte Perkins Gilman’s writing called, â€Å"The Yellow Wallpaper.† There are many similarities and differences between both Victorian women’s perspectives and writing. This paper will compare and contrast the short stories written by Kate Chopin and CharlotteRead MoreKate Chopin s The Yellow Wallpaper And The Story Of An Hour1887 Words   |  8 Pagesword coming out of their mouths. Two out of the ordinary shor t stories, â€Å"The Yellow Wallpaper† and â€Å"The Story of An Hour,† mostly focused on a women’s dilemma that they faced near the 19th century. The two main characters in the short stories show some resemblances in some ways, but both characters portrayed them in different ways of how they dealt their sorrows in their marriages. â€Å"The Story of An Hour† by Kate Chopin is about a woman named Louise Mallard, who was very unsatisfied with her marriageRead MoreAnalysis Of Kate Chopin s The Story Of An Hour And The Yellow Wallpaper 721 Words   |  3 Pages102 Assignment 8 Part 2 Literary Analysis October 29, 2017 Longing for Freedom How much would you sacrifice to have the ability to make your own decisions? Would you risk your sanity or even your life? â€Å"The Story of an Hour† by Kate Chopin and â€Å"The Yellow Wallpaper† by Charlotte Perkins Gilman both illustrate the feeling of wanting to escape and gaining freedom. Both stories are about a woman who is oppressed by her husband and trying to find a way to overcome this depression. These stories areRead MoreKate Chopin s An Hour, And Tillie Olsen s `` The Yellow Wallpaper ``1150 Words   |  5 Pagesbenefit economically, socially, politically, culturally, and several more ways. This essay will highlight and analyze the cultural aspects of feminism from the texts of Kate Chopin’s novel The Awakening, Donald Hall’s â€Å"Feminist Analysis† from Literary and Cultural Theory, Charlotte Gilman’s short story †The Yellow Wallpaper†, Kate Chopin’s short story â€Å"The Story of an Hour†, and Til lie Olsen’s short story â€Å"Tell Me A Riddle.† Cultural feminism, the ideology of the roles and stereotypical characteristicsRead MoreKate Chopin s An Hour, And Tillie Olsen s `` The Yellow Wallpaper ``1396 Words   |  6 Pagesmultiple theories on feminism, Donald Hall’s definition of cultural feminism, from his â€Å"Feminist Analysis† of Literary and Cultural Theory, will be used to explore the cultural aspects of the texts from Kate Chopin’s novel The Awakening, Charlotte Gilman’s short story †The Yellow Wallpaper,† Kate Chopin’s short story â€Å"The Story of an Hour†, and Tillie Olsen’s short story â€Å"Tell Me A Riddle.† The ideology of feminism is that women are unable to express themselves due to being oppressed by patriarchalRead MoreKate Chopin s An Hour, And Tillie Olsen s `` The Yellow Wallpaper ``1483 Words   |  6 Pagesbenefit economically, socially, politically, culturally, and s everal more ways. This essay will highlight and analyze the cultural aspects of feminism from the texts of Kate Chopin’s novel The Awakening, Donald Hall’s â€Å"Feminist Analysis† from Literary and Cultural Theory, Charlotte Gilman’s short story †The Yellow Wallpaper†, Kate Chopin’s short story â€Å"The Story of an Hour†, and Tillie Olsen’s short story â€Å"Tell Me A Riddle.† Cultural feminism, the ideology of the roles and stereotypical characteristicsRead More Freedom for Women in The Yellow Wallpaper by Charlotte Perkins Gillman and The Story of an Hour by Kate Chopin1202 Words   |  5 PagesFreedom for Women in The Yellow Wallpaper by Charlotte Perkins Gillman and The Story of an Hour by Kate Chopin The Yellow Wallpaper by Charlotte Perkins Gillman and The Story of an Hour by Kate Chopin are two feminist works in which liberation is the overlying theme. Both of the main characters achieve freedom from their husbands oppression in these short stories; however, freedom is only achieved through insanity in The Yellow Wallpaper and death in The Story of an Hour. The womenRead More Theme of Entrapment in The Awakening and The Yellow Wallpaper1239 Words   |  5 PagesEntrapment in The Awakening and The Yellow Wallpaper Topics of great social impact have been dealt with in many different ways and in many different mediums. Beginning with the first women’s movement in the 1850’s, the role of women in society has been constantly written about, protested, and debated. Two women writers who have had the most impact in the on-going women’s movement are Kate Chopin and Charlotte Perkins Gilman. The Awakening and The Yellow Wallpaper are two of feminist literature’sRead More Oppression of Women in Chopins Story of an Hour and Gilmans Yellow Wallpaper 1246 Words   |  5 PagesOppression of Women in Chopins Story of an Hour and Gilmans Yellow Wallpaper    The Story of an Hour by Kate Chopin and The Yellow Wallpaper by Charlotte Perkins Gilman share the same view of the subordinate position of women in the late 1800s. Both stories demonstrate the devastating effects on the mind and body that result from an intelligent person living with and accepting the imposed will of another. This essay will attempt to make their themes apparent by examining a brief summeryRead More Womens Issues in The Awakening by Kate Chopin, The Yellow Wallpaper by Charlotte Perkins Gilman, and Souls Belated by Edith Wharton1028 Words   |  5 PagesWomens Issues in The Awakening by Kate Chopin, The Yellow Wallpaper by Charlotte Perkins Gilman, and Souls Belated by Edith Wharton In comparing the three authors and the literary works of women authors Kate Chopin (1850 -1904), The Awakening, Charlotte Perkins Gilmans (1860-1935), The Yellow Wallpaper, and Edith Whartons (1862-1937) Souls Belated, a good number common social issues related to women are brought to light and though subtly pointed out are an outcry against the conventions

Lovastatin and Tumor Necrosis Factor

Question: Discuss about the Lovastatin and Tumor Necrosis Factor. Answer: Introduction: Heart diseases are common. According to the University of Minnesota, John Hunter, a great physician in the eighteenth centurypainted the medical image of angina pectoris in order to explainhow suddendeaths occur. The account of coronary disorders, stroke, and sudden death can be traced back to ancient times and how specialists have treated it thoroughly from different disciplines(Means 2012). It is in this light that the following discussion will cover a widely used medicine to prevent heart attacks and diseases known as Lovastatin. Lovastatin is scientifically known as(HMG-CoA) Hydroxymethylglutaryl-coenzyme A.It is a reductase and an enzyme that limits the rate in the cholesterol biosynthetic pathway. It also lowers the cholesterol in the body. This drug was the first HMG-CoA reductaseinhibitor that was used in treating hypercholesterolemia. This is aprescription drug available in the form of an immediate release tablet as well as extended release tablet. Lovastatin prescription is a combination therapy whereby it is accompanied together with weight loss, exercise, and diet, in order to decrease the menace of stroke and heart attack. In addition, it is used to moderate the quantity of cholesterol in the blood by slackening the production of cholesterol to cut a numberoffacts that may accumulate on the arterial walls and block the flow of blood to the heart, brains, and other parts of the body. Primary administration Lovastatin is administered in the evening. The drug is taken orally. This is a tradition that been followed by many physicians. This comes from the fact that cholesterol biosynthesis hepatic HMG-CoA reductase is highest at night and the half-life of statins is usually very short. Lovastatin has half-lives of sixhours or less. For maximum lowering of LDL, lovastatin has to be administered in the evening. This is important to exhibit these enzymes when they are mostly active. After carrying out a study, it was realized that when administering this drug in the evening there were high chances of reducing cholesterol than when compared to administering it during the day(Lewis 2014). Taking of statins in the morning can lead to the rise of cholesterol and low level of lipoprotein. Cholesterol levels are usually very high in the morning and are highest in the afternoon. For a patient who is mostly awake at night, the medication intake of lovastatin is carried after twelve hours of work. The drug should be taken as directed without taking more or less of it or often than the doctors prescription. The tablet should be swallowed whole without splitting, chewing or crushing it and a patient should only stop using the tablet after talking with his/her doctor. Many are times when medicine have allergic reactions on our bodies hence it is crucial to disclose allergies to certain medication or any ingredients in lovastatin. Therefore, it is very important for one to follow instructions when using the drug (Leibowitz 2010).When on lovastatin medication the patient should not tale alcohol , the patient should also avoid taking a lot of grapejuice, this is because the risks of the side effects can be increased. Lovastatin reduces the effects of the following drugs when taken together. These drugs include: ketoconazole, intraconazole, nefazodone, HIV inhibitors, blood thinners, some of cholesterol lowering drugs such as niacin and gemfibrozil. One should inform the doctor on the medication they are on to avoid such risks Lovastatin is hydrolyzed to lactone in vivo. In pharmacokinetics studies, the inhibition of HMG-CoA is usually the basis of this study. After lovastatin was administered orally in a man, .10% of this drug was in urine while 83% was excreted in feces. Excretion in feces indicates that the drug was absorbed and excreted in bile and the presence of theunabsorbed drug. The concentration of plasma of the lovastatin metabolites was high after 2 hours of dosage and declined to 10% after 24hours of dosage. After oral dosage, lovastatin highly selected the liver where it had high concentration than its target tissues. Lovastatin usually undergoes high selectivity of the liver where it was more concentrated than in the target tissues. Extensive first-pass extraction usually happens in the liver. There is also subsequent of the drug equivalent in the bile. Due totheextensive hepatic extraction of this drug, its availability to circulate as active inhibitor is very low. Lovastatin is highly boun d to plasma proteins in humans. This drug crosses the placenta and blood-brain barriers. The most active metabolites in the human plasma are -hydroxyacid of Lovastatin, and two other metabolites(Due and Wroblewski2013). Mechanism of action The liver usually controls hypercholesterolemia and Dyslipidemia. An increase of the LDL receptor can cause the decrease in the levels of cholesterol. Lovastatin is meant to inhibit HMG-CoA reductase.This is the enzymethatchanges HMG-CoA to mevalonic acid. The statin competes withthesubstrate in the active sites of the enzymes. Lovastatin works by stamping down fatty acids and cholesterol in the body. Reduction of this cholesterol can lead to the prevention of vascular disease, heart failure, and strokes. The statin works in the liver in order so as to prevent or inhibit HMG-CoA reductase. After discharging bad cholesterol from the liver, it is discharged in the blood artery vessels. Therefore, the lovastatin works to lower the cholesterol so that they fats cannot clog up the arteries (Herrick 2012). Lovastatin is used in treating coronary heart diseases.It prevents both secondary and primary effects on the heart. The drug is used in managing cardiovascular risk in individuals with levels of plasma cholesterol that are normal. Lovastatin is also used in treating patients that have progressive renal diseases. Application of lovastatin has proved to slow renal function loss and in the prevention of cretonne clearance decline. Lovastatin is used in treating cancer. In the inhabitation of cell growth, the drug may be independent of Ras function. In the bone fraction treatment, it works by stimulating the formation of bones in vivo and invitro. When administered in long doses it leads to the healing of bone fractures. The drug is used in the inhibition of the nitric oxide (Riekes et al. 2017). Therefore, it is important for patients to use the drug only under the doctors prescription and the patient should stop using the drug incase the above side effect is experienced. Lovastatin as a therapy drug Lovastatin belongs to a therapy class. Lovastatin belongs to a class of therapy known as the statins. Statins are administered so as to reduce cholesterol that is found in the blood .This is done by blocking the enzyme that is required to make cholesterol. It is used in treating heart diseases by lowering the cholesterollevel. It is not an anti-inflammatory drug.It is a therapy drug, which is associated with asymptomatic and mild elevations. These elevations are brought by higher dosage of lovastatin (Liu et al. 2017). Just like most medical drugs, lovastatin has its own side effects, which are grouped into side effects that are common and side effects that are serious. The side effects that are common occur with the use of lovastatin areapain in the abdomen (stomach area), heartburn, nausea, headache, constipation, memory loss, confusion, insomnia, muscle pain and lack of energy in the body (Fye 2014). The serious side effects and their symptoms may include muscle problem where one experiences muscle pain, tenderness, and weakness. In addition, the drug leads to liver problems, which make one pass urine dark in color and yellowing skin, or eyes turn white.It also causes the problem of the central nervous system, which is characterized byalack of energy, weakness, and extreme tiredness. In addition, one may experience flu- like symptoms that are, body aches, fever, tiredness, cough, and hoarseness, also, bleeding problems may be experienced with symptoms like unusual bleeding and bruising (Joseph M ajd2012). Therefore, it is very important for patients using this drug to seek immediate medical attention if the above discussed side effects prolong. References List Joseph, L, Majd, A 2012, 'A brief review: history to understand fundamentals of electrocardiography', Journal Of Community Hospital Internal Medicine Perspectives, Vol 2, Iss 1, Pp 1-5 (2012), viewed 30 March 2017. Retrieved from https://doaj.org/article/34c8a98d7c3e4a51a353c92ee7b31881 Fye, W. B. 2014. A history of the origin, evolution and impact of electrocardiography. The American Journal of Cardiology 73 (13):937-949. Herrick, J. B. 2012. Certain clinical features of sudden obstruction of the coronary arteries. Journal of the American Medical Association 27:100-116. La Due, J. S., and F. Wroblewski. 2013. The significance of serum glutamic oxalacetic transaminase activity following acute myocardial infarction. Circulation 2:871-877. Leibowitz, J. O. 2010. The history of coronary heart disease. Berkeley: University of California Press Lewis, T.2014. Diseases of the heart. 4th ed. London: Macmillan. Means, J. H. 2012. The Association of American Physicians: Its first seventy-five years. New York: McGraw-Hill. Liu, P.C., Lu, G., Deng, Y., Wang, C.D., Su, X.W., Zhou, J.Y., Chan, T.M., Hu, X. and Poon, W.S., 2017. Inhibition of NF-B Pathway and Modulation of MAPK Signaling Pathways in Glioblastoma and Implications for Lovastatin and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) Combination Therapy.PloS one,12(1), p.e0171157. Riekes, M.K., Dereymaker, A., Berben, P., Augustijns, P., Stulzer, H.K. and Van den Mooter, G., 2017. Development of enteric-coated fixed dose combinations of amorphous solid dispersions of ezetimibe and lovastatin: Investigation of formulation and process parameters.International journal of pharmaceutics,520(1), pp.49-58. Langert, K.A., Goshu, B. and Stubbs, E.B., 2017. Attenuation of experimental autoimmune neuritis with locally administered lovastatin?encapsulating poly (lactic?co?glycolic) acid nanoparticles.Journal of Neurochemistry,140(2), pp.334-346.

To Kill Or Not To Kill Essays - Crime, Misconduct,

To Kill Or Not To Kill Capital punishment has been in effect since the 1600's (Cole 451). However, in 1972 the U.S. Supreme Court ruled that the death penalty was cruel and unusual punishment, which was unconstitutional according to the Eighth amendment. It was public opinion that the current methods of execution, hanging, electrocution, and facing a firing squad, were too slow and painful upon the person to be executed (Cole 451). The U.S. Supreme Court reversed this decision when a cleaner way to bring about death was found in 1976. This cleaner way is death by lethal injection, which is quick and painless if administered right (Cole 450). Since capital punishment has been reinstituted many people have argued for and against capital punishment. Some say the death penalty is what the criminal deserves while others object to it because death is irreversible. I feel the death penalty is a good form of justice because only about 250 people a year get the death penalty and they are guilty beyond a doubt and d on't deserve living with the possibility of parole. The sentencing judge or jury are ordered by the Supreme Court to look for specific aggravating and mitigating factors in deciding which convicted murderers should be sentenced to death (Cole 451). Some of these mitigating factors are the defendant's motivation, character, personal history, and most of all remorse (Costanzo). Every year approximately 250 new offenders are added to death row. In 1994 there were 2,850 persons awaiting execution. Yet no more than thirty-eight people have been executed a year since 1976. This is a ridiculously low number compared to 199 persons executed in 1935 (all from Cole 451). The reason for this slow execution rate is the process of appeals, from sentencing to execution there is about a seven to eight year wait. The convict's cases' are reviewed by the state courts and through the federal courts (Cole 451). With all this opportunity for the case to be turned over or the sentence to be changed it is almost impossible for an innocent person to be executed. Only two people have been proved innocent after their execution in the United States. These wrongful deaths occurred in 1918 and 1949 (Death Penalty Discussion). Since then the justice system has undergone a lot of fine tuning making this extremely unlikely today. One argument against the death penalty is that it costs less to imprison someone for life than to execute them (Death Penalty Discussion). This is a good point that has a lot of impact on a lot of peoples views regarding capital punishment since they are the ones footing the bill through taxes. I personally would not mind paying the little bit extra just so I know for sure that there's one less murderer on our planet. If the death penalty was done away with, prisoners who should have been executed will be mixed in with other inmates. It would be possible and not too unlikely for them to kill another inmate or possibly a prison guard. If someone is lined up for execution then they more than likely deserve it. They have caused a great deal of grief to the family and friends of the victim or victims and it seems like the only way justice could be served is for the criminal to die. For the person to simply go to jail seems unfair. There they will eat three meals a day, get to watch cable t.v., and befriend other inmates. They live a pretty decent life in prison and they don't deserve it. Out of the fifty states in the United States 37 have and use capital punishment. Out of the same fifty states only 18 have life imprisonment with out parole. In the other 32 states a person who should've been executed can be released after as little as 20 years in prison (Death Penalty). There are certain standards that are followed in giving out capital punishment. The defendant can not be insane, and the mans rea or criminal intent must be present. Also, minors very rarely receive the death penalty because they are not fully mature and might not know the consequences of their actions. Finally the mentally retarded are very